Drug Title

Lotrisone (Clotrimazole and Betamethasone)

Application

Lotrisone is used to treat certain fungal skin infections including ringworm, fungal infections and itchiness. It also relieves redness and itching associated with infection.

Mode of application

Use Lotrisone as prescribed by your doctor. Follow the instructions on the label.

Wash your hands before and after applying Lotrisone. Shake well before each use.

Before applying the medication, clean and dry the affected area.

Carefully treat the damaged skin till the drug is evenly distributed.

Treating the groin, wear loose clothing.

Lotrisone is most effective when used on a regular basis. To clean up your infection completely, the full course of Lotrisone treatment is needed. Keep using it even if you feel better within a few days.

Bandage the affected area unless directed otherwise by your doctor.

If you are using Lotrisone in the groin area, use it no more than 2 weeks and apply the lotion sparingly. Wear loose clothing. Tell your doctor if the condition persists for 2 weeks.

The mechanism of action

Lotrisone is an antifungal and corticosteroid combination. It works by weakening cell membranes of some fungi. It also acts as an anti-inflammatory and anti-itch agent.

Missed dose

If you miss a dose of Lotrisone, use it as soon as possible. If it occurred while taking your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

The cream should be stored between 20 and 30 degrees Celsius (36-86 degrees Fahrenheit).

Precautions

Do not use lotion Lotrisone, if:

• you are allergic to any ingredient in Lotrisone Lotion;
• you are taking pimozide or ergot alkaloids (e.g. ergotamine).

Contact the doctor immediately if any of the items apply to you.

Some medicines may interact with Lotrisone Lotion. Tell your doctor if you have any medical conditions, especially from the list below, that apply to you:

• if you are pregnant, planning to become pregnant or are breast-feeding;
• If you are taking any nonprescription medicines, herbal preparations or dietary supplements;
• if you have allergies to medicines, foods or other substances;
• If you have a diaper rash, eczema, measles, tuberculosis (TB) or a positive test for lupus, chickenpox, shingles or thinning of the skin;
• If you have recently had vaccinations.

Some medicines may interact with Lotrisone Lotion. Tell your doctor if you are taking any other medicines, especially any from the list below:

• Clarithromycin as the risk of certain side effects may be increased;
• Barbiturates (e.g. phenobarbital), carbamazepine, hydantoins (e.g. phenytoin) or rifampin as they may decrease the effectiveness of Lotrisone Lotion;
• Ergot alkaloids (e.g. ergotamine), imatinib, live vaccines, macrolide immunosuppressants (e.g. tacrolimus), pimozide or ritodrine as they can increase the risk of side effects;
• Hydantoins (e.g. phenytoin) or interleukin-2 as their effectiveness may be reduced by the use of Lotrisone Lotion.

This may not be a complete list of all interactions that may occur. Ask your doctor about possible Lotrisone Lotion interactions with other medications you are taking. Consult the doctor before you start taking, stop or change the dose of any medicine.

Side effects

Consult the doctor if any of the most common side effects persist or become frequent:

• Dry skin, mild stinging or burning sensation at the application site.

Seek medical help immediately if any of the serious side effects occur:

• Severe allergic reactions (rash, hives, itching, shortness of breath, chest tightness, swelling of the mouth, face, lips, or tongue), irritation, redness, blistering, swelling, oozing or severe burns at the application site and unusual bruising.

Additional information

If you have any questions about Lotrisone Lotion, please talk to your doctor.
Lotrisone lotion should be used strictly on prescription.
If symptoms do not improve or aggravate, consult the doctor.